NEW YORK (AP) – Luis Castillo pitched five-hit ball into the seventh inning in his Seattle debut, and the Mariners used a fast start to beat Gerrit Cole and the New York Yankees 7-3 on Wednesday. Eugenio SuÃ¡rez, Carlos Santana and Jarred Kelenic homered against Cole (9-4) during Seattle’s six-run first. Jesse Winker connected against Wandy Peralta in the seventh, helping the Mariners match their season high for homers. Castillo (5-4) struck out eight in 6 2/3 innings in his second start in the Bronx in less than a month. The right-hander allowed three runs and walked three. The 29-year-old Castillo was acquired by Seattle in a trade with Cincinnati on Friday night for four prospects. Kyle Higashioka hit a two-run homer for the Yankees. PHILLIES 3, BRAVES 1 ATLANTA (AP) – Nick Castellanos hit a tiebreaking two-run homer in the eighth inning as Philadelphia took full advantage of an overturned call. The Phillies looked to be down to their final three outs when J.T. Realmuto grounded into what was ruled an inning-ending double play with the Braves nursing a 1-0 lead. But Philadelphia challenged the call, and the replay showed Realmuto’s foot getting to the bag ahead of the relay throw while Rhys Hoskins trotted home from third. With the game now tied at 1, Collin McHugh (2-2) fell behind 2-0 in the count before grooving one to Castellanos, who connected for his ninth homer. Zack Wheeler (10-5) pitched seven innings for the win. David Robertson, acquired Tuesday in a trade with the Chicago Cubs, worked a scoreless ninth for his first Philadelphia save. Orlando Arcia homered for Atlanta, which had won four straight. METS 9, NATIONALS 5 WASHINGTON (AP) – Daniel Vogelbach hit a grand slam for the Mets, and Pete Alonso connected for his 28th homer. New York won for the eighth time in nine games and opened a 3Â½-game lead over second-place Atlanta in the NL East. The teams begin a four-day, five-game series Thursday in New York. Chris Bassitt (8-7) pitched seven shutout innings for New York, which finished with 14 hits. Washington lost for the fifth time in seven games a day after it traded star outfielder Juan Soto and first baseman Josh Bell to San Diego. Keibert Ruiz and Lane Thomas homered during the Nationals’ five-run ninth. AnÃbal SÃ¡nchez (0-4) surrendered five runs – four earned – in 4 1/3 innings. ASTROS 6, RED SOX 1 HOUSTON (AP) – Trey Mancini homered in his first start for Houston, and Jose Urquidy struck out 10 in seven scoreless innings. Mancini hit a two-run drive in the second against Rich Hill (4-5), lifting the Astros to a 4-0 lead. Mancini was acquired in a trade with Baltimore on Monday and then grounded out as a pinch hitter in his Astros debut Tuesday night. Urquidy (10-4) allowed two hits and walked none. Jose Altuve tied a career high with four hits to help Houston avoid a sweep after losing the first two games of the series. Xander Bogaerts homered for Boston in the ninth. ORIOLES 6, RANGERS 3 ARLINGTON, Texas (AP) – Pinch-hitter Terrin Vavra lined a tiebreaking RBI double right after a disputed stolen base in the eighth inning, and the Orioles completed their first season series sweep against Texas. The Rangers challenged when Jorge Mateo was ruled safe on a stolen base with two outs, and the call stood after a replay review of the bang-bang play. Vavra then doubled into left-center for a 3-2 lead, and Robinson Chirinos singled him home with his third hit. Chirinos and Ryan McKenna homered for the Orioles (54-51), who swept all three games in Texas like they did at home a month ago. Cionel PÃ©rez (6-1) got the win.